LACIE ADP/PI joint case study: ADP analysis guidelines

The procedure is described which was used to train automatic data processing (ADP) analysts to process ERTS 1 imagery from a 5 nm by 6 nm area in Delisle, Canada, and to estimate wheat acreage using training fields provided by photointerpreters. The exercise also served to evaluate and test current large area crop inventory experiment (LACIE) procedures

Feasibility study ASCS remote sensing/compliance determination system

A short-term technical study was performed by the MSC Earth Observations Division to determine the feasibility of the proposed Agricultural Stabilization and Conservation Service Automatic Remote Sensing/Compliance Determination System. For the study, the term automatic was interpreted as applying to an automated remote-sensing system that includes data acquisition, processing, and management

Microwave ISM Emission in the Green Bank Galactic Plane Survey: Evidence for Spinning Dust

We observe significant dust-correlated emission outside of H II regions in the Green Bank Galactic Plane Survey (-4 < b < 4 degrees) at 8.35 and 14.35 GHz. The rising spectral slope rules out synchrotron and free-free emission as majority constituents at 14 GHz, and the amplitude is at least 500 times higher than expected thermal dust emission. When combined with the Rhodes (2.326 GHz), and WMAP (23-94 GHz) data it is possible to fit dust-correlated emission at 2.3-94 GHz with only soft synchrotron, free-free, thermal dust, and an additional dust-correlated component similar to Draine & Lazarian spinning dust. The rising component generally dominates free-free and synchrotron for \nu >~ 14 GHz and is overwhelmed by thermal dust at \nu > 60 GHz. The current data fulfill most of the criteria laid out by Finkbeiner et al. (2002) for detection of spinning dust.Comment: ApJ in press. 26 pages, 11 figures, figures jpeg compressed to save spac

DISSECTING THE ROLES OF TRIM24 IN REGULATION OF HEPATIC LIPID METABOLISM AND INFLAMMATION

DISSECTING THE ROLES OF TRIM24 IN REGULATION OF HEPATIC LIPID METABOLISM AND INFLAMMATION Lindsey Cauthen Minter, B.S., B.A. Advisory Professor: Michelle C. Barton, Ph.D. In this dissertation, I report the characterization of a new mouse model that recapitulates development of hepatocellular carcinoma (HCC) following spontaneous hepatic lipid accumulation, inflammation, and damage of liver tissue, due to complete loss of Trim24 expression. In human HCC and other cancers, TRIM24 expression is aberrantly high, while deletion of TRIM24 in the mouse has been shown to act as a liver specific tumor suppressor. The hypothesis tested here was that TRIM24, the E3 ubiquitin ligase of p53, regulates genes that impact hepatic lipid inflammation and metabolism. I further dissected whether TRIM24 regulates immune cell populations that are commonly misregulated in nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). In the first part of my dissertation, I establish through global gene expression, chromatin enrichment, biochemical, and immunohistochemical analyses that TRIM24 represses hepatic lipid accumulation, inflammation, and fibrosis and damage in the murine liver. In the second part of my thesis, I show that loss of Trim24 leads to increased hepatic macrophage populations and implicates crosstalk with the hematopoietic niche in the bone marrow. Intersections of RNA-seq and TRIM24 ChIP-seq datasets yielded novel gene targets of TRIM24 in mouse liver. Furthermore, I show that TRIM24 is enriched at promoters of genes involved in oxidative stress control, inflammation, and glucose metabolism, all processes that are misregulated in NAFLD and NASH progression. Further, biochemical analyses showed increased glucose metabolism and insulin sensitivity coupled with a decrease in visceral adipose tissue upon loss of Trim24. These findings recapitulate those found in human studies of lean (non-obese) individuals with NAFLD. Thus, this dissertation shows that complete loss of Trim24 offers a model of nonalcoholic fatty liver disease, steatosis, fibrosis and development of hepatocellular carcinoma in the absence of high-fat diet or obesity. In addition, this model offered an opportunity to identify specific immune cell populations, gene targets and metabolic pathways that are regulated by TRIM24

Estimation of the Probability of Error without Ground Truth and Known A Priori Probabilities

The probability of error or, alternatively, the probability of correct classification (PCC) is an important criterion in analyzing the performance of a classifier. Labeled samples (those with ground truth) are usually employed to evaluate the performance of a classifier. Occasionally, the numbers of labeled samples are inadequate, or no labeled samples are available to evaluate a classifier\u27s performance; for example, when crop signatures from one area from which ground truth is available are used to classify another area from which no ground truth is available. This paper reports the results of an experiment to estimate the probability of error using unlabeled test samples (i.e., without the aid of ground truth)

Social Connectedness in Different Relationship Contexts

While an overwhelming majority of teens still spend time with their friends in person at least occasionally, people have become increasingly reliant on technology for communication and maintaining feelings of social connectedness. Social connectedness is a sense of belonging to an individual or group characterized by satisfaction, perceived level of support, and opportunities for self-disclosure within a particular relationship context. There is consistent evidence that online communication does not foster the same degree of closeness as offline interactions, largely due to the lack of indirect forms of communication like non-verbal cues and tone of voice (Scott et al., 2022a). Offline relationships encourage deeper self-disclosure and allow both parties to utilize indirect forms of communication like non-verbal cues to better communicate thoughts, feelings, and ideas (Scott et al., 2022a). However, there is also evidence that paired online and offline communication can facilitate even stronger relationships than one centered around one relationship context (Winstone et al., 2021). In this study, we will be surveying approximately 60 students enrolled in one of the Fall 2022 sections of Belmont University’s PSY1200 Introduction to Psychological Science course. Participants will complete the Inclusion of Others in the Self Scale (IOS) Scale to assess feelings of closeness and connection to friends in three different relationship contexts: online, in-person, and mixed-mode (both online and in-person) (Aron, et al., 1992). We hypothesize that participants will feel the highest level of connectedness in their mixed-mode platonic relationship. We are currently collecting data and results will be presented at SURS

A 42.3-43.6 GHz spectral survey of Orion BN/KL: First detection of the v=0 J=1-0 line from the isotopologues 29SiO and 30SiO

We have surveyed molecular line emission from Orion BN/KL from 42.3 to 43.6 GHz with the Green Bank Telescope. Sixty-seven lines were identified and ascribed to 13 different molecular species. The spectrum at 7 mm is dominated by SiO, SO2, CH3OCH3, and C2H5CN. Five transitions have been detected from the SiO isotopologues 28SiO, 29SiO, and 30SiO. We report here for the first time the spectra of the 29SiO and 30SiO v=0 J=1-0 emission in Orion BN/KL, and we show that they have double-peaked profiles with velocity extents similar to the main isotopologue. The main motivation for the survey was the search of high-velocity (100-1000 km/s) outflows in the BN/KL region as traced by SiO Doppler components. Some of the unidentified lines in principle could be high-velocity SiO features, but without imaging data their location cannot be established. Wings of emission are present in the v=0 28SiO, 29SiO and 30SiO profiles, and we suggest that the v=0 emission from the three isotopologues might trace a moderately high-velocity (~30-50 km/s) component of the flows around the high-mass protostar Source I in the Orion BN/KL region. We also confirm the 7 mm detection of a complex oxygen-bearing species, acetone (CH3COCH3), which has been recently observed towards the hot core at 3 mm, and we have found further indications of the presence of long cyanopolyynes (HC5N and HC7N) in the quiescent cold gas of the extended ridge.Comment: 27 pages, 3 figures, accepted by Ap

Maximizing Payload Mass Fractions of Spacecraft for Interplanetary Electric Propulsion Missions

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76389/1/AIAA-17433-786.pd